Sunday, August 30, 2026
Professor Jon Stone - Functional Neurological Disorder (FND) and MS - looking for a treatable cause of disability
Why do people get functional neurological disorders? - DR R GRUNEWALD ; Sheffield Teaching Hospitals NHS Foundation Trust
DR MATTHEW PHILLIPS (WAIKATO, NZ) ON FUNCTIONAL NEUROLOGICAL DISORDERS
RECOGNISING FUNCTIONAL SEIZURES - PROF JON STONE
MYTHBUSTER - FND IS FAKE
WELLWORKS CATALOG
THE .PDF CATALOG OF PRODUCTS RE CANANBIS
https://drive.google.com/file/d/1iWcimCMmAuVREjm_qnmw05C227Hskf1X/view?usp=sharing
No area of stroke research should be left behind
More than 12 million incident cases of stroke are thought
to have occurred in 2019, when stroke was also the
second-leading cause of death and the third-leading cause
of death and disability combined. Thanks to the efforts of
stroke researchers and study participants, many advances
that might help to reduce this burden have been made
over the past two decades. Much of this progress has
been in acute management and secondary prevention of
ischaemic stroke, and as this issue of The Lancet Neurology
was going to press, results from several trials testing
such approaches were scheduled to be presented at the
8th European Stroke Organisation Conference (ESOC),
on May 4–6, 2022, in Lyon, France. If such progress is to
continue, and similarly impressive advances are to be
made in primary prevention, haemorrhagic stroke, and
longer-term care, all areas of stroke need to be a higher
priority for research funding.
https://drive.google.com/file/d/1eGQds8AyZjDQXgkdnjDX8UgqCWX88ZTA/view?usp=sharing
The use of amantadine in catatonia
We read with interest the excellent
Personal View by Olivier Rascol and
colleagues on the use of amantadine
in Parkinson’s disease and other
movement disorders.1
One movement
disorder for which amantadine
has shown some benefit but the
authors did not mention is catatonia.
Catatonia is a neuropsychiatric
syndrome that occurs in association
with psychiatric disorders such as
schizophrenia and bipolar disorder,
and also various neurological diseases,
including autoimmune encephalitis.
Characteristic clinical signs include
stupor, mutism, posturing, catalepsy,
echophenomena, mannerisms,
stereotypies, and negativism.
Catatonia has been associated
with substantial morbidity and
complications, including pneumonia,
acute kidney injury, and pulmonary
embolus.
https://drive.google.com/file/d/1EVEua8i4HrJighmDezUBaBIs3NOnw9aq/view?usp=sharing
FND Functional Neurological Disorder in Aotearoa/NZ 3.4.24
THIS IS A POWER POINT USED IN CONFERENCE WITH NEUROLOGIST M PHILLIPS AND THE HEAD OF MEDICINE IN 2023
https://drive.google.com/file/d/1ZgLKSDnjE9Ss85-rT5xQWTbRr2CJEoMM/view?usp=sharing
HOW TO MANAGE CRPS FLARES
MANAGIN PAIN IS DIFFICULT, HERE IS A GUIDE TO METHODS USED BY PATIENTS
https://drive.google.com/file/d/1bOVskQ_qScDKdf_dgSWqkfZSWWJ3j0rm/view?usp=drive_link
Functional neurological disorder: new subtypes and shared mechanisms
Functional neurological disorder is common in neurological practice. A new approach to the positive diagnosis of this
disorder focuses on recognisable patterns of genuinely experienced symptoms and signs that show variability within
the same task and between different tasks over time. Psychological stressors are common risk factors for functional
neurological disorder, but are often absent. Four entities—functional seizures, functional movement disorders,
persistent perceptual postural dizziness, and functional cognitive disorder—show similarities in aetiology and
pathophysiology and are variants of a disorder at the interface between neurology and psychiatry. All four entities have
distinctive features and can be diagnosed with the support of clinical neurophysiological studies and other biomarkers.
The pathophysiology of functional neurological disorder includes overactivity of the limbic system, the development of
an internal symptom model as part of a predictive coding framework, and dysfunction of brain networks that gives
movement the sense of voluntariness. Evidence supports tailored multidisciplinary treatment that can involve physical
and psychological therapy approaches.
https://drive.google.com/file/d/1EnFs_fM6wZ-rLjU0LrMSAsTxy5hPKC7j/view?usp=drive_link
FND AS A SECONDARY CONDITION
Functional neurological disorder (FND) is a complex condition that is caused
by various triggers and presents itself in unique ways differing from person to
person. Someone with FND might present with similar symptoms as someone
with a Stroke, Parkinson’s Disease or Epilepsy for example. However, instead
of it being structural, it is functional – a disconnect between the brain sending
signals, and the body receiving them. As well, people with FND can also have
epilepsy and other comorbidities. The mind/body connection can get “glitchy”
and has trouble processing sensory inputs and emotional overload. This
sometimes happens randomly on a neurological level, sometimes there is a
(direct correlation between the trigger and symptom - cause/effect) stress
trigger, which can be causing an overwhelming amount of any emotion, and
sometimes it’s a sensory overload in the environment which causes physical
or mental symptoms. This does not mean that symptoms are psychological
and that this is a mental disorder or “attention seeking behaviour” as that is
outdated understandings and simply inaccurate according to new research
and observation. Behaviour means having a choice to do something, these
symptoms are not chosen by the person with FND however are reactions to
stress and overwhelm. Some common symptoms may include arm and leg
weakness, seizures, fainting, ticks, tremors, intense pain, and the list may go
on and on for some people. The nervous system generally can be on high
alert and hypersensitive to triggers. That is, until the person’s stress bucket is
emptied enough and equipped with enough coping skills to manage. (Written
by Katerina Giovos, 2023).
https://drive.google.com/file/d/15t4eCe9ij7-NQnLliZ3Qq3SjyZfsihLS/view?usp=drive_link
Correction to Lancet Neurol 2022; 21: 125–39
In this Article, in the Summary, the
number of countries in which the
trials were done should be 18. In the
Outcomes section of Methods, the
prespecified efficacy endpoints “change
from baseline in subjective WASO and
latency to sleep onset (LSO) at months
1 and 3” should be deleted as they are
not reported. In the Statistical analysis
section of Methods, .....
https://drive.google.com/file/d/1kXO8xIHI4aw_dOGwVKKTV57eOYLQ4UtC/view?usp=drive_link
Neuroimmunology: In-Depth Description
Neuroimmunology is the study of the complex, bidirectional interactions between the central nervous system (CNS) and the immune system. Traditionally, researchers viewed these two complex networks as entirely separate entities, operating under the assumption that the brain was strictly "immune-privileged" and isolated from systemic immune responses. Today, neuroimmunology investigates how immune cells, cytokines, and inflammatory processes influence neurological development, brain function, and disease pathogenesis, as well as how the nervous system regulates immune function throughout the body.
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Doctors treated her symptoms, offered different diagnoses, and tried various approaches, yet nothing fully explained what she was experien...
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Neuroimmunology is the study of the complex, bidirectional interactions between the central nervous system (CNS) and the immune system. Tr...
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1. Introduction Functional neurological disorder (FND) is a condition at the neurology-psychiatry interface that impacts individuals acros...