Showing posts with label MEDICAL ARTICLE. Show all posts
Showing posts with label MEDICAL ARTICLE. Show all posts
Sunday, August 30, 2026
Professor Jon Stone - Functional Neurological Disorder (FND) and MS - looking for a treatable cause of disability
RECOGNISING FUNCTIONAL SEIZURES - PROF JON STONE
WORLD RESPECTED NEUROLOGIST, PROFESSOR JON STONE
ON
RECOGNISING FUNCTIONAL SEIZURES
MYTHBUSTER - FND IS FAKE
FUNCTIONAL NEUROLOGICAL DISORDER IS OFTEN DISMISSED AS FAKE OR FICTICIOUS DISORDER
No area of stroke research should be left behind
More than 12 million incident cases of stroke are thought
to have occurred in 2019, when stroke was also the
second-leading cause of death and the third-leading cause
of death and disability combined. Thanks to the efforts of
stroke researchers and study participants, many advances
that might help to reduce this burden have been made
over the past two decades. Much of this progress has
been in acute management and secondary prevention of
ischaemic stroke, and as this issue of The Lancet Neurology
was going to press, results from several trials testing
such approaches were scheduled to be presented at the
8th European Stroke Organisation Conference (ESOC),
on May 4–6, 2022, in Lyon, France. If such progress is to
continue, and similarly impressive advances are to be
made in primary prevention, haemorrhagic stroke, and
longer-term care, all areas of stroke need to be a higher
priority for research funding.
https://drive.google.com/file/d/1eGQds8AyZjDQXgkdnjDX8UgqCWX88ZTA/view?usp=sharing
The use of amantadine in catatonia
We read with interest the excellent
Personal View by Olivier Rascol and
colleagues on the use of amantadine
in Parkinson’s disease and other
movement disorders.1
One movement
disorder for which amantadine
has shown some benefit but the
authors did not mention is catatonia.
Catatonia is a neuropsychiatric
syndrome that occurs in association
with psychiatric disorders such as
schizophrenia and bipolar disorder,
and also various neurological diseases,
including autoimmune encephalitis.
Characteristic clinical signs include
stupor, mutism, posturing, catalepsy,
echophenomena, mannerisms,
stereotypies, and negativism.
Catatonia has been associated
with substantial morbidity and
complications, including pneumonia,
acute kidney injury, and pulmonary
embolus.
https://drive.google.com/file/d/1EVEua8i4HrJighmDezUBaBIs3NOnw9aq/view?usp=sharing
FND Functional Neurological Disorder in Aotearoa/NZ 3.4.24
THIS IS A POWER POINT USED IN CONFERENCE WITH NEUROLOGIST M PHILLIPS AND THE HEAD OF MEDICINE IN 2023
https://drive.google.com/file/d/1ZgLKSDnjE9Ss85-rT5xQWTbRr2CJEoMM/view?usp=sharing
HOW TO MANAGE CRPS FLARES
MANAGIN PAIN IS DIFFICULT, HERE IS A GUIDE TO METHODS USED BY PATIENTS
https://drive.google.com/file/d/1bOVskQ_qScDKdf_dgSWqkfZSWWJ3j0rm/view?usp=drive_link
Correction to Lancet Neurol 2022; 21: 125–39
In this Article, in the Summary, the
number of countries in which the
trials were done should be 18. In the
Outcomes section of Methods, the
prespecified efficacy endpoints “change
from baseline in subjective WASO and
latency to sleep onset (LSO) at months
1 and 3” should be deleted as they are
not reported. In the Statistical analysis
section of Methods, .....
https://drive.google.com/file/d/1kXO8xIHI4aw_dOGwVKKTV57eOYLQ4UtC/view?usp=drive_link
Neuroimmunology: In-Depth Description
Neuroimmunology is the study of the complex, bidirectional interactions between the central nervous system (CNS) and the immune system. Traditionally, researchers viewed these two complex networks as entirely separate entities, operating under the assumption that the brain was strictly "immune-privileged" and isolated from systemic immune responses. Today, neuroimmunology investigates how immune cells, cytokines, and inflammatory processes influence neurological development, brain function, and disease pathogenesis, as well as how the nervous system regulates immune function throughout the body.
Saturday, August 29, 2026
Neuroscience rotation gives student a chance to explore brainy interests
The Akakpo-Ulloa Family Neuroscience Scholarship is designed to foster interest in neurology and psychiatry, and provide exposure to multidisciplinary care.
He Had Up to Seventy-Eight Sneezing Attacks a Day, and the Fix Was in His Arm
They looked exactly like sneezes. Repeated contractions of the diaphragm, Forced exhalation through the nose, tic-like rhythmic vocalizations layered on top. Strong smells often set them off, though they could also arrive at random.
They were not sneezes.
A 32-year-old teacher reached a functional neurological disorder clinic having lived with them for nine years. At presentation, the attacks were lasting up to 10 minutes and coming several times a day, reaching a maximum of 78 episodes. He reported episodes that woke him at night, though without a sleep study, clinicians could not confirm whether they occurred in true sleep or early wakefulness.
https://www.medicaldaily.com/functional-sneeze-functional-movement-disorder-case-report-477880
Friday, August 28, 2026
Brain imaging research is thriving in functional neurological disorder
1. Introduction
Functional neurological disorder (FND) is a condition at the neurology-psychiatry interface that impacts individuals across the lifespan (Hallett et al., 2022). The conceptualization of FND in the 20th century was fraught with dualistic perspectives of brain versus mind – exemplified by outdated terms such as “hysteria” and “psychogenic”. Structure and function are closely coupled in the human brain, and neuroimaging research in FND provides an opportunity to bridge the science of brain and mind in this prevalent and potentially disabling condition (Finkelstein et al., 2025, O’Mahony et al., 2023). Advancing the neuroscience of FND further erodes artificial distinctions between brain health and mental health – and offers the potential to develop novel mechanistically-informed treatments.
https://www.sciencedirect.com/science/article/pii/S221315822600063X
Functional Neurologic Disorder (NIH)
What is functional neurologic disorder?
Functional neurologic disorder (FND) refers to a neurological condition caused by changes in how brain networks work, rather than changes in the structure of the brain itself, as seen in many other neurological disorders. Physical symptoms of FND are genuine but cannot be explained by changes in the brain structure. The exact cause of FND is unknown.
https://www.ninds.nih.gov/health-information/disorders/functional-neurologic-disorder
Functional neurological disorder: Practical management (SCIENCE DIRECT)
Functional Neurological Disorder (FND) is a common and disabling condition seen by nearly every clinician in nearly every clinical setting. There are multiple subtypes with seizure and motor/movement being the most common. There is high health care utilization and costs, and many patients have a chronic course and remain disabled. It is clear from research over the past two decades that abnormalities in brain network activity are implicated in the pathophysiology of FND. Diagnosis requires positive criteria and knowing how to obtain a good history and avoid common pitfalls. There are evidence-based treatments and expert consensus recommendations. A multidisciplinary team knowledgeable about the disorder is important for the best outcomes but there is much more work to be done. This review will focus on the practical aspects of diagnosing and managing FND.
https://www.sciencedirect.com/science/article/pii/S187874792500090X
FND GUIDE
FND describes neurological symptoms like limb weakness, tremor, numbness or blackouts, related to the movement and sensation parts of the nervous system…..
- Caused by a PROBLEM with the FUNCTIONING of the nervous system
- A “software” issue of the brain, not the hardware (as in stroke or MS)
- With positive diagnostic features typical of FND
- Cause day to day difficulties for the person who experiences them
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