Thursday, August 27, 2026

Genetic and Early-Life Vulnerability in Functional Neurological Disorder: A Large-Scale Retrospective Cohort Study

 Functional neurological disorder (FND) is a common and disabling condition with diverse presentations, such as motor (weakness, tremor, dystonia, gait), sensory, cognitive, and seizure-like symptoms, often in combination.1 It is understood as a disorder of brain network dysfunction, in which the brain generates overly strong predictions about body states that override incoming sensory and motor signals, and symptoms arise from this mismatch.2 Historically, FND has been conceptualised in terms of psychological stress or traumatic experiences, often arising in childhood.3 However, contemporary models situate it within a broader biopsychosocial framework, in which early-life biological influences are poorly characterised compared to psychosocial factors. Previously reported inherited and......


https://www.emjreviews.com/neurology/abstract/genetic-and-early-life-vulnerability-in-functional-neurological-disorder-a-large-scale-retrospective-cohort-study-j11126/

No comments:

Post a Comment

Tell us what's new

Note: Only a member of this blog may post a comment.

Practical FND Management: Daily Life Hacks

FND LIFE HACKS BY FND AWARE NZ